Combined Liquid Based Cervical Cytology and High-Risk HPV mRNA for Cervical Cancer Screening in Thammasat Hospital

Cervical cancer is the second most common type of malignancy found in Thai women, only preceded by breast cancer (IARC 2015). Early detection of cervical cancer can decrease its incidence. Implementation of an effective organized screening in the target population is highly desirable by providing coverage of adequate screening intervals. It can also provide an effective and reliable means for investigating women with abnormal screening results. Definite diagnosis will insure that appropriate measure can be given to the patient in timely manner. It is now understood that human papillomavirus (HPV) infection is a major cause of cervical cancer (Thomas et al., 2014). Only a minor fraction of all HPV infection will progress to precancerous lesions and cancer. Over 200 different HPV genotypes are described and classified to high risk (HR) and low risk (LR) group. The most often